Sodium Stearyl Fumarate CAS 4070-80-8
Sodium Stearyl Fumarate is a white fine powder. Soluble in methanol, almost insoluble in water. Sodium Stearyl Fumarate is obtained by reacting stearic alcohol with maleic anhydride, isomerizing the reaction product into a salt. Sodium Stearyl Fumarate is a hydrophilic lubricant used as a lubricant in pharmaceutical excipients. It can overcome many problems related to magnesium stearate, such as affecting the main drug and excessive lubrication; Forming a protective film in effervescent tablets can improve disintegration, promote dissolution, and thus increase bioavailability.
Item | Specification |
melting point | >196°C (dec.) |
Storage conditions | Inert atmosphere,Room Temperature |
purity | 98% |
LogP | 8.789 (est) |
colour | White to off white |
Sodium stearate fumarate (C22H39NaO4) is a widely used and important pharmaceutical and food excipient. During the metabolic process of sodium fumarate in animals, most of it can be absorbed and hydrolyzed to produce stearic alcohol and stearic acid. A small portion can be directly and quickly metabolized, and it is non-toxic and non irritating. In the pharmaceutical field, sodium stearate fumarate is added to drug formulations as a lubricant for tablets and capsules. Chemicalbook can also form a protective film in effervescent tablets, which can solve the problems of stearate lubricants and improve drug disintegration and promote drug dissolution. In the food industry, the FDA allows sodium fumarate stearate to be directly added as a regulator and stabilizer to food intended for human consumption, such as various baked goods, flour thickened foods, dried potatoes, and processed grains. The amount of sodium fumarate added can account for 0.2-1.0% of the weight of the food.
Usually packed in 25kg/drum,and also can be do customized package.
Sodium Stearyl Fumarate CAS 4070-80-8
Sodium Stearyl Fumarate CAS 4070-80-8