One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong
One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong Detail:
Purple-brown needle crystal, melting point 147℃, optical rotation αD20=+135°(benzene). Soluble in phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, animal and vegetable oils and alkaline aqueous solutions, insoluble in water. The hue changes with the Ph value, with a Ph value of 4-6 being red, a Ph value of 8 being purple, and a Ph value of 10-12 being blue. Good light resistance, heat resistance and oxidation resistance, unstable to reducing dose, and dark purple in case of iron ions. Has a certain antibacterial effect.
| CAS | 517-89-5 |
| Other Names | Shikonine |
| Appearance | purple powder |
| Purity | 99% |
| Color | purple |
| Storage | Cool Dried Storage |
| Package | 25kg/bag |
| Application | Food |
(1) Hypoglycemic effect The leaf extract of comfrey and the polysaccharide (A, B, C) of comfrey have obvious hypoglycemic effect.
(2) Bacteriostatic effect Lithospermum has an inhibitory effect on Jingke 68-1 virus in vitro, and has an inhibitory effect on Staphylococcus aureus. The anti-parainfluenza virus effect of levoshikonin was studied by hemagglutination reaction and cytopathic method. The results showed that it had low toxicity within the concentration range used in the experiment, and had certain in vitro anti-influenza virus activity and direct killing of parainfluenza virus. effect.
(3) Effects on blood coagulation: Intraperitoneal injection of shikonin components (shikonin, acetylshikonin) does not affect blood coagulation time, but can prevent the anticoagulant effect of heparin.
(4) Anti-tumor effect Comfrey extract has a certain inhibitory effect on the late stage (G2 phase) of DNA synthesis in Hela cells.
(5) Antitumor effect Shikonin inhibits proliferation, promotes apoptosis and induces cell cycle arrest in cultured human choriocarcinoma drug-resistant cell lines (JAR/MTX) in vitro. Experiments show that the concentration of shikonin increases with the dose. And the prolongation of the action time, the inhibition rate of the growth of choriocarcinoma drug-resistant cells also increased significantly.
(6) Effects on hormone secretion The effect of shikonin on the function of the hypothalamic-pituitary-gonadal axis in adolescent female rats showed that the serum hormone levels in the shikonin group were significantly lower than those in the negative control group, and there was no significant difference compared with the positive control group. different. It shows that shikonin can inhibit the function of hypothalamic-pituitary-gonadal axis in rats.
(7) Antioxidant effect Some researchers measured the scavenging ability of shikonin to superoxide radical (O2-) and 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), and its effect on β- – Inhibition of the carotene/linoleic acid autoxidation system. The results showed that shikonin had strong scavenging ability to DPPH and O2-, and had obvious inhibitory effect on the auto-oxidation system of β-carotene/linoleic acid. Strong antioxidant capacity.
25kgs/drum,9tons/20’container
Product detail pictures:
Related Product Guide:
Dedicated to strict quality management and thoughtful client services, our experienced staff customers are generally available to discuss your demands and guarantee full client pleasure for One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong , The product will supply to all over the world, such as: Muscat, Jordan, Austria, we always keep our credit and mutual benefit to our client, insist our high quality service to moving our clients. always welcome the our friends and clients to come and visit our company and guid our business, if you are interested in our products, you can also submit your purchase information online, and we will contact you immediately, we keep our highly sincere cooperation and wish everything in your side are all well.
By Darlene from Iceland - 2017.06.19 13:51
Managers are visionary, they have the idea of "mutual benefits, continuous improvement and innovation", we have a pleasant conversation and Cooperation.
By Stephanie from Algeria - 2018.11.02 11:11
