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One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong


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One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong Detail:

Purple-brown needle crystal, melting point 147℃, optical rotation αD20=+135°(benzene). Soluble in phenethyl ether, acetone, chloroform, methanol, ethanol, glycerol, animal and vegetable oils and alkaline aqueous solutions, insoluble in water. The hue changes with the Ph value, with a Ph value of 4-6 being red, a Ph value of 8 being purple, and a Ph value of 10-12 being blue. Good light resistance, heat resistance and oxidation resistance, unstable to reducing dose, and dark purple in case of iron ions. Has a certain antibacterial effect.

CAS 517-89-5
Other Names Shikonine
Appearance purple powder
Purity 99%
Color purple
Storage Cool Dried Storage
Package 25kg/bag
Application Food

(1) Hypoglycemic effect The leaf extract of comfrey and the polysaccharide (A, B, C) of comfrey have obvious hypoglycemic effect.

(2) Bacteriostatic effect Lithospermum has an inhibitory effect on Jingke 68-1 virus in vitro, and has an inhibitory effect on Staphylococcus aureus. The anti-parainfluenza virus effect of levoshikonin was studied by hemagglutination reaction and cytopathic method. The results showed that it had low toxicity within the concentration range used in the experiment, and had certain in vitro anti-influenza virus activity and direct killing of parainfluenza virus. effect.

(3) Effects on blood coagulation: Intraperitoneal injection of shikonin components (shikonin, acetylshikonin) does not affect blood coagulation time, but can prevent the anticoagulant effect of heparin.

(4) Anti-tumor effect Comfrey extract has a certain inhibitory effect on the late stage (G2 phase) of DNA synthesis in Hela cells.

(5) Antitumor effect Shikonin inhibits proliferation, promotes apoptosis and induces cell cycle arrest in cultured human choriocarcinoma drug-resistant cell lines (JAR/MTX) in vitro. Experiments show that the concentration of shikonin increases with the dose. And the prolongation of the action time, the inhibition rate of the growth of choriocarcinoma drug-resistant cells also increased significantly.

(6) Effects on hormone secretion The effect of shikonin on the function of the hypothalamic-pituitary-gonadal axis in adolescent female rats showed that the serum hormone levels in the shikonin group were significantly lower than those in the negative control group, and there was no significant difference compared with the positive control group. different. It shows that shikonin can inhibit the function of hypothalamic-pituitary-gonadal axis in rats.

(7) Antioxidant effect Some researchers measured the scavenging ability of shikonin to superoxide radical (O2-) and 1,1-diphenyl-2-picrophenhydrazine radical (DPPH), and its effect on β- – Inhibition of the carotene/linoleic acid autoxidation system. The results showed that shikonin had strong scavenging ability to DPPH and O2-, and had obvious inhibitory effect on the auto-oxidation system of β-carotene/linoleic acid. Strong antioxidant capacity.

25kgs/drum,9tons/20’container


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One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong detail pictures

One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong detail pictures

One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong detail pictures


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Our business puts emphasis over the administration, the introduction of talented staff, plus the construction of employees building, striving hard to boost the standard and liability consciousness of staff members. Our corporation successfully attained IS9001 Certification and European CE Certification of One of Hottest for 119-61-9 - SHIKONIN CAS 517-89-5 Shikonine – Unilong , The product will supply to all over the world, such as: Bulgaria, New York, Estonia, We offer OEM services and replacement parts to meet the varying needs of our customers. We offer competitive price for quality products and we will make certain your shipment is handled quickly by our logistics department. We sincerely hope to have the opportunity to meet with you and see how we can help you further your own business.
  • This company has the idea of "better quality, lower processing costs, prices are more reasonable", so they have competitive product quality and price, that's the main reason we chose to cooperate.
    5 Stars By Page from Ecuador - 2018.09.21 11:01
    It can be said that this is a best producer we encountered in China in this industry, we feel lucky to work with so excellent manufacturer.
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