(R)-Lactate, CAS number is 10326-41-7. It also has some common aliases, such as (R)-2-hydroxypropionic acid, D-2-hydroxypropionic acid, etc. The molecular formula of D-lactic acid is C₃H₆O₃, and the molecular weight is about 90.08. Its molecular structure is characterized by the fact that lactic acid is the smallest chiral molecule in nature. The carbon atom at the α position of the carboxyl group in the molecule is an asymmetric carbon atom with two configurations, L (+) and D (-), and the D-lactic acid here is right-handed. (R)-Lactate has the typical chemical properties of monocarboxylic acids. Its aqueous solution is weakly acidic. When the concentration reaches more than 50%, it will partially form lactic anhydride, react with some alcohol substances to form alkyd resin, and can undergo intermolecular esterification under heating conditions to form lactyl lactic acid (C₆H₁₀O₅). It can be hydrolyzed into D-lactic acid after dilution and heating. In addition, under the action of the dehydrating agent zinc oxide, two molecules of (R)-Lactate remove two molecules of water and self-polymerize to form a cyclic dimer D-lactide (C₆H₈O₄, DLA), which can form polymerized (R)-Lactate after sufficient dehydration. Since the more concentrated the lactic acid, the stronger its tendency to self-esterification, lactic acid is usually a mixture of lactic acid and lactide.
(R) -Lactate appears as a colorless to slightly yellow clear viscous liquid at room temperature and pressure. It smells slightly sour and is hygroscopic. Its aqueous solution will show an acidic reaction. It has good solubility and can be mixed with water, ethanol or ether at will, but it is insoluble in chloroform. In terms of physical parameters, its density (20/20℃) is between 1.20~1.22g/ml, its melting point is 52.8°C, its boiling point is 227.6°C, its vapor pressure is 3.8Pa at 25℃, its flash point is 109.9±16.3 °C, its refractive index is about 1.451, and its molecular weight is about 90.08, and its solubility in water is H₂O: 0.1 g/mL.
(R)-Lactate CAS 10326-41-7 is suitable for storage in a cool and dry place, and should be kept away from light. It is not suitable for outdoor storage. At the same time, it needs to be stored away from strong alkaline substances and strong oxidants to ensure its stability and enable it to be better stored and used.
Important uses of D-lactic acid
Medical field
(R)-Lactate CAS 10326-41-7 has important application value in the medical field. It is a key raw material or intermediate for the synthesis of many drugs. As a chiral center, (R)-Lactate CAS 10326-41-7 with high optical purity (more than 97%) is the precursor of many chiral substances and plays an indispensable role in the pharmaceutical industry. For example, it can be used to produce calcium antagonist antihypertensive drugs, which have a good effect on controlling hypertension. By acting on the cardiovascular system, it helps regulate blood pressure levels and provides strong support for the treatment of hypertensive patients.
Chemical industry
(R)-Lactate CAS 10326-41-7 plays a very important role in the chemical industry. Lactic acid esters produced with (R)-Lactate CAS 10326-41-7 as raw material are widely used in the production process of many chemical products such as fragrances, synthetic resin coatings, adhesives and printing inks.
Degradable materials
D-lactic acid is an important raw material for bioplastic polylactic acid (PLA), which has far-reaching significance for the development of degradable materials. Polylactic acid, as a new type of bio-based and renewable biodegradable material, is made from starch raw materials extracted from renewable plant resources (such as corn, cassava, etc.), which is in line with the current concept of environmental protection and sustainable development.
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Post time: Dec-19-2024