ATP disodium salt CAS 987-65-5

CAS: 987-65-5

Purity: 99%

Molecular Formula: C10H17N5NaO13P3

Molecular Weight: 531.18

EINECS: 213-579-1

Storage Period: 2 years

Synonyms: ADENOSINETRIPHOSPHATEDISODIUM; ADENOSINETRIPHOSPHATE,DISODIUMSALT; ADENYLPYROPHOSPHORICACIDDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATEHYDRATEDISODIUMSALT; ADENOSINE-5′-TRIPHOSPHATENA2-SALT; ADENOSINE-5′-TRIPHOSPHORICACID,DISODIUM; ADENOSINE-5′-TRIPHOSPHORICACIDDISODIUMDIHYDROGENSALT; ADENOSINE5′-TRIPHOSPHORICACIDDISODIUMSALT

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What is ATP disodium salt CAS 987-65-5?

ATP disodium salt is a metabolite of adenosine, a multifunctional nucleoside triphosphate that is used as a coenzyme for intracellular energy transfer in cells. It transports chemical energy within cells for metabolism. ATP disodium salt is used to synthesize ribose-modified deoxyadenosine diphosphate analogs as P2Y1 receptor ligands.

Specification

Appearance	White powder or off- white powder or crystal powder, hygroscopic.
Particle size	＞95% pass through 80 mesh.
pH	2.5～3.5
Solubility	Soluble in water; insoluble in ethanol & ether.
Oder	Oderless
Water content	6.0%~12.0%
Chloride	≤0.05%
Iron salt	≤0.001%
Heavy metals	≤0.001%
Lead	≤2.0ppm
Arsenic	≤1.0ppm

Application

1. Industrial and scientific research uses
(1) Cosmetic raw materials: added to anti-aging skin care products, it can improve skin elasticity and glossiness by activating cell energy metabolism.
(2) Food additives: used as a nutritional enhancer in sports drinks and functional foods to quickly replenish energy.
2. Clinical treatment areas
(1) Cardiovascular system diseases: used for heart failure, myocarditis, myocardial infarction and cerebral arteriosclerosis, etc., by improving myocardial energy metabolism and dilating coronary arteries (increasing blood flow by about 30%), relieving myocardial ischemia symptoms. For example, in patients with acute myocardial infarction, ATP disodium can shorten the ST segment fall time and reduce the peak value of myocardial enzyme spectrum.
(2) Nervous system diseases: auxiliary treatment of sequelae of cerebral hemorrhage, brain damage and progressive muscular atrophy, by penetrating the blood-brain barrier (permeability is about 65%), promoting nerve cell membrane repair and nerve process regeneration, and improving nerve conduction velocity.
(3) Metabolic diseases: In the treatment of hepatitis and cirrhosis, ATP disodium can enhance the mitochondrial activity of hepatocytes, accelerate hepatocyte repair, and reduce ALT and AST levels; it also has an auxiliary improvement effect on diabetic complications (such as peripheral neuropathy).
3. Emerging application areas
(1) Targeted drug delivery system: ATP disodium can be used as a carrier modifier, combined with liposomes or nanoparticles, to achieve targeted drug delivery through receptor-mediated endocytosis. For example, in tumor treatment, ATP-modified nanomedicines can improve the selective killing efficiency of chemotherapy drugs on cancer cells.
(2) Cell culture and biopharmaceuticals: As a key component of cell culture medium, ATP disodium can promote the growth and protein expression of CHO cells, HEK293 cells, etc., and is widely used in monoclonal antibody production.